6RA5

TNIK (TRAF2 and NCK-interacting protein kinase)
Group: STE
Uniprot: TNIK_HUMAN
Organism: Homo sapiens
Domain boundary: 25 - 289
Resolu: 2.9

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Active DFGin BLAminus in-in in-in JWE Type1 12 - 309 0
B None DFGin BLAminus in-none in-in No_ligand No_ligand 14 - 310 7
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain B
        18         28         38         48 
gsdeiDLSAL RDPAGIFELV ELVGNGTYGQ VYKGRHVKTG 
        58         68         78         88 
QLAAIKVMDV TGDEEEEIKQ EINMLKKYSH HRNIATYYGA 
        98        108        118        128 
FIKKNppGMD DQLWLVMEFC GAGSVTDLIK NTKGNTLKEE 
       138        148        158        168 
WIAYICREIL RGLSHLHQHK VIHRDIKGQN VLLTENAEVK 
       178        188        198        208 
LVDFGVSAQl drtvgrRNTF IGTPYWMAPE VIACDEnpda 
       218        228        238        248 
tYDFKSDLWS LGITAIEMAE GAPPLCDMHP MRALFLIPRN 
       258        268        278        288 
PAPRLKSKKW SKKFQSFIES CLVKNHSQRP ATEQLMKHPF 
       298        308 
IRDQPNERQV RIQLKDHIDR TKkkrg
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: X181,X187