6P8E

CDK4 (Cyclin-dependent kinase 4)
Group: CMGC
Uniprot: CDK4_HUMAN
Organism: Homo sapiens
Domain boundary: 6 - 295
Resolu: 2.3

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
B Inactive DFGin None out-out none-none No_ligand No_ligand 18 - 299 15
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain B
         8         18         28         38 
gefatsryep vaeigvgayG TVYKARDPHS GHFVALKSVR 
        51         61         71         81 
VPNGEEGLPI STVREVALLR RLEAFEHPNV VRLMDVCATS 
        91        101        111        121 
rtdrEIKVTL VFEHVDQDLR TYLDKAPPPG LPAETIKDLM 
       131        141        151        161 
RQFLRGLDFL HANCIVHRDL KPENILVTSG GTVKLADFGL 
       171        181        191        201 
ariysyqmal tpvvvTLWYR APEVLLQSTY ATPVDMWSVG 
       211        221        231        241 
CIFAEMFRRK PLFCGNSEAD QLGKIFDLIG LPPEDDWPRD 
       251        261        271        281 
VSLPRGAFPP RGPRPVQSVV PEMEESGAQL LLEMLTFNPH 
       291        301 
KRISAFRALQ HSYLHKDEgn pe
Lower-case residues are disordered in structure.
Mutations: G43E,G47E
Phosphorylation: None