6P5S

HIPK2 (Homeodomain-interacting protein kinase 2)
Group: CMGC
Uniprot: HIPK2_HUMAN
Organism: Homo sapiens
Domain boundary: 199 - 527
Resolu: 2.194

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Active DFGin BLAminus in-in in-in 3NG Type1 185 - 535 6
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
         -        177        187        197 
mgsshhhhhh ssgenlyfqg snsegdyQLV QHEVLCSMTN 
       207        217        227        237 
TYEVLEFLGR gtfGQVVKCW KRGTNEIVAI KILknhpsya 
       247        257        267        277 
RQGQIEVSIL ARLSTESADD YNFVRAYECF QHknHTCLVF 
       287        297        307        317 
EMLEQNLYDF LKQNKFSPLP LKYIRPVLQQ VATALMKLKS 
       327        337        347        357 
LGLIHADLKP ENIMLVDPSR QPYRVKVIDF GSASHVskav 
       367        377        387        397 
csTYLQSRYY RAPEIILGLP FCEAIDMWSL GCVIAELFLG 
       407        417        427        437 
WPLYPGASEY DQIRYISQTQ GLPAEYLLSA GTKTTRFFNR 
       447        457        467        477 
DTDSPYPLWR LKTPDDHEAE TGIKSKEARK YIFNCLDDMA 
       487        497        507        517 
QVNMTTDLEG SDMLVEKADR REFIDLLKKM LTIDADKRIT 
       527        537        547 
PIETLNHPFV TMTHLLDFph sthvkscfqn
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: X361,X441