6JUX

ACVR1 (Activin receptor type-1)
Group: TKL
Uniprot: ACVR1_HUMAN
Organism: Homo sapiens
Domain boundary: 208 - 497
Resolu: 1.75

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin BLAminus in-out in-in C9U Type1 203 - 499 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
       210        220        230        240 
qrTVAHQITL LECVGKGRYG EVWRGSWQGE NVAVKIFSSR 
       250        260        270        280 
DEKSWFRETE LYNTVMLRHE NILGFIASDM TSRHSSTQLW 
       290        300        310        320 
LITHYHEMGS LYDYLQLTTL DTVSCLRIVL SIASGLAHLH 
       330        340        350        360 
IEIFGtqGKP AIAHRDLKSK NILVKKNGQC CIADLGLAVM 
       370        380        390        400 
HSQSTNQLDV GNNPRVGTKR YMAPEVLDET IQVDCFDSYK 
       410        420        430        440 
RVDIWAFGLV LWEVARRMVS NGIVEDYKPP FYDVVPNDPS 
       450        460        470        480 
FEDMRKVVCV DQQRPNIPNR WFSDPTLTSL AKLMKECWYQ 
       490 
NPSARLTALR IKKTLTKID
Lower-case residues are disordered in structure.
Mutations: R206H
Phosphorylation: None