6GGH

JAK1 (Tyrosine-protein kinase JAK1)
Group: TYR
Uniprot: JAK1_HUMAN
Organism: Homo sapiens
Domain boundary: 875 - 1153
Resolu: 1.7

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin ABAminus in-in in-in EYQ Type1 865 - 1154 0
B Inactive DFGin ABAminus in-in in-in EYQ Type1 863 - 1154 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain B
       872        882        892        902 
TEVDPTHFEK RFLKRIRDLG EGHFGKVELC RYDPEGDNTG 
       912        922        932        942 
EQVAVKSLkp esgGNHIADL KKEIEILRNL YHENIVKYKG 
       952        962        972        982 
ICTedggnGI KLIMEFLPSG SLKEYLPKNK NKINLKQQLK 
       992       1002       1012       1022 
YAVQICKGMD YLGSRQYVHR DLAARNVLVE SEHQVKIGDF 
      1032       1042       1052       1062 
GLTKAIETDK EYYTVKDDRD SPVFWYAPEC LMQSKFYIAS 
      1072       1082       1092       1102 
DVWSFGVTLH ELLTYCDSDS SPMALFLKMI GPTHGQMTVT 
      1112       1122       1132       1142 
RLVNTLKEGK RLPCPPNCPD EVYQLMRKCW EFQPSNRTSF 
      1152 
QNLIEGFEAL LK
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: X1034,X1035