6ELR

JAK1 (Tyrosine-protein kinase JAK1)
Group: TYR
Uniprot: JAK1_HUMAN
Organism: Homo sapiens
Domain boundary: 875 - 1153
Resolu: 1.8

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin ABAminus in-in in-in BFK Type1 854 - 1154 0
B Inactive DFGin ABAminus in-in in-in BFK Type1 865 - 1154 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain B
       863        873        883        893 
divsekkpat eVDPTHFEKR FLKRIRDLGE GHFGKVELCR 
       903        913        923        933 
YDPEGDNTGE QVAVKSLKPe sggnHIADLK KEIEILRNLY 
       943        953        963        973 
HENIVKYKGI CTEdggNGIK LIMEFLPSGS LKEYLPKNKN 
       983        993       1003       1013 
KINLKQQLKY AVQICKGMDY LGSRQYVHRD LAARNVLVES 
      1023       1033       1043       1053 
EHQVKIGDFG LTKAIETDKE YYTVKDDRDS PVFWYAPECL 
      1063       1073       1083       1093 
MQSKFYIASD VWSFGVTLHE LLTYCDSDSS PMALFLKMIG 
      1103       1113       1123       1133 
PTHGQMTVTR LVNTLKEGKR LPCPPNCPDE VYQLMRKCWE 
      1143       1153 
FQPSNRTSFQ NLIEGFEALL K
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: X1034,X1035