6E9W

ROCK1 (Rho-associated protein kinase 1)
Group: AGC
Uniprot: ROCK1_HUMAN
Organism: Homo sapiens
Domain boundary: 76 - 338
Resolu: 2.96

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin ABAminus in-in in-in J0P Type1 9 - 404 0
B Inactive DFGin ABAminus in-in in-out J0P Type1 7 - 401 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain B
         -          -          -         12 
msyyhhhhhh dydipttenl yfqgamdplv prgsFETRFE 
        22         32         42         52 
KMDNLLRDPK SEVNSDCLLD GLDALVYDLD FPALRKNKNI 
        62         72         82         92 
DNFLSRYKDT INKIRDLRMK AEDYEVVKVI GRGAFGEVQL 
       102        112        122        132 
VRHKSTRKVY AMKLLSKFEM ikrsdsAFFW EERDIMAFAN 
       142        152        162        172 
SPWVVQLFYA FQDDRYLYMV MEYMPGGDLV NLMSNYDVPE 
       182        192        202        212 
KWARFYTAEV VLALDAIHSM GFIHRDVKPD NMLLDKSGHL 
       222        232        242        252 
KLADFGTCMK MNKEGMVRCD TAVGTPDYIS PEVLKSQggd 
       262        272        282        292 
GYYGRECDWW SVGVFLYEML VGDTPFYADS LVGTYSKIMN 
       302        312        322        332 
HKNSLTFPDD NDISKEAKNL ICAFLTDREV RLGRNGVEEI 
       342        352        362        372 
KRHLFFKNDQ WAWETLRDTV APVVPDLSSD IDTSNFDDLE 
       382        392        402        412 
edkgeeETFP IPKAFVGNQL PFVGFTYYSn rrylssanpn 

dnr
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None