6E6E

SRC (Proto-oncogene tyrosine-protein kinase Src)
Group: TYR
Uniprot: SRC_HUMAN
Organism: Homo sapiens
Domain boundary: 270 - 521
Resolu: 2.15

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Active DFGin BLAminus in-in in-in HVY Type1 261 - 536 10
B Active DFGin BLAminus in-in in-in HVY Type1.5_Back 261 - 536 10
C Active DFGin BLAminus in-in in-in HVY Type1 261 - 536 10
D Active DFGin BLAminus in-in in-in HVY Type1 261 - 536 10
E Active DFGin BLAminus in-in in-in HVY Type1.5_Back 261 - 536 10
F Active DFGin BLAminus in-in in-in HVY Type1 261 - 536 10
G Inactive DFGin BLAminus in-out in-in HVY Type1.5_Back 261 - 536 12
H Active DFGin BLAminus in-in in-in HVY Type1 261 - 536 12
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain H
       270        280        290        300 
DAWEIPRESL RLEVKLGQGC FGEVWMGTWN GTTRVAIKTL 
       310        320        330        340 
KPGTMSPEAF LQEAQVMKKL RHEKLVQLYA VVSEEPIYIV 
       350        360        370        380 
TEYMSKGSLL DFLKGETGKY LRLPQLVDMA AQIASGMAYV 
       390        400        410        420 
ERMNYVHRDL RAANILVGEN LVCKVADFGL ARLIedneyt 
       430        440        450        460 
arqgakFPIK WTAPEAALYG RFTIKSDVWS FGILLTELTT 
       470        480        490        500 
KGRVPYPGMV NREVLDQVER GYRMPCPPEC PESLHDLMCQ 
       510        520        530 
CWRKEPEERP TFEYLQAFLE DYFTSTEPQY QPGENL
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None