6DUD

JAK3 (Tyrosine-protein kinase JAK3)
Group: TYR
Uniprot: JAK3_HUMAN
Organism: Homo sapiens
Domain boundary: 822 - 1111
Resolu: 1.66

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Active DFGin BLAminus in-in in-in HB4 Type1 814 - 1100 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
       813        823        833        843 
mghhhhhhqd PTIFEERHLK YISQLGKGNF GSVELCRYDP 
       853        863        873        883 
LGDNTGALVA VKQLQhsGPD QQRDFQREIQ ILKALHSDFI 
       893        903        913        923 
VKYRGVSYgp grqsLRLVME YLPSGCLRDF LQRHRARLDA 
       933        943        953        963 
SRLLLYSSQI CKGMEYLGSR RCVHRDLAAR NILVESEAHV 
       973        983        993       1003 
KIADFGLAKL LPLDKDYYVV REPGQSPIFW YAPESLSDNI 
      1013       1023       1033       1043 
FSRQSDVWSF GVVLYELFTY CDKSCSPSAE FLRMMgcerd 
      1053       1063       1073       1083 
vpALSRLLEL LEEGQRLPAP PACPAEVHEL MKLCWAPSPQ 
      1093       1103       1113       1123 
DRPSFSALGP QLDMLWSgsr gcethaftah pegkhhslsf 

s
Lower-case residues are disordered in structure.
Mutations: C1048S
Phosphorylation: None