6CMJ

CAMKK2 (Calcium/calmodulin-dependent protein kinase kinase 2)
Group: CAMK
Uniprot: KKCC2_HUMAN
Organism: Homo sapiens
Domain boundary: 165 - 446
Resolu: 2.4

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Active DFGin BLAminus in-in in-in F6J Type1 161 - 463 0
B Active DFGin BLAminus in-in in-in F6J Type1 161 - 462 0
Representative sequence - Chain B
- 149 159 169
mnahhhhhhg saenlyfqgh hvsitgmqdc vQLDQYTLKD
179 189 199 224
EIGKGSYGVV KLAYNENDNT YYAMKVLSKK KLIRQAGGCI
234 244 254 264
QPRGPIEQVY QEIAILKKLD HPNVVKLVEV LDDPNEDHLY
274 284 294 304
MVFELVNQGP VMEVPTLKPL SEDQARFYFQ DLIKGIEYLH
314 324 334 344
YQKIIHRDIK PSNLLVGEDG HIKIADFGVS NEFKGSDALL
354 364 374 384
SNTVGTPAFM APESLSETRK IFSGKALDVW AMGVTLYCFV
394 404 414 424
FGQCPFMDER IMCLHSKIKS QALEFPDQPD IAEDLKDLIT
434 444 454 464
RMLDKNPESR IVVPEIKLHP WVTRHGAEPL PSEDENCTlv

e
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: X345,X400,X462