CAMKK2 (Calcium/calmodulin-dependent protein kinase kinase 2)

Group: CAMK
Uniprot: KKCC2_HUMAN
Domain boundary: 165 - 446


Total number of chains: 20
Spatial Dihedral Chains Representative
DFGin BLAminus 20 AF-Q96RR4-K1A
Representatives from each cluster
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

PDB Resolution Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Mutation Phosphorylation Unresolved residues in A-loop
AF-Q96RR4-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 157 - 454 None None 0
6CMJA 2.4 Active DFGin BLAminus in-in in-in F6J Type1 161 - 463 None X345,X400,X462 0
6CMJB 2.4 Active DFGin BLAminus in-in in-in F6J Type1 161 - 462 None X345,X400,X462 0
5UY6A 1.7 Active DFGin BLAminus in-in in-in 8R4 Type1 161 - 448 None None 0
5UYJA 1.6 Active DFGin BLAminus in-in in-in 8R7 Type1 161 - 449 None None 0
5VT1A 1.9 Active DFGin BLAminus in-in in-in 9JS Type1 161 - 448 None None 0
6BKUA 2.0 Active DFGin BLAminus in-in in-in DXV Type1 162 - 448 None None 0
6BLEA 1.9 Active DFGin BLAminus in-in in-in 34U Type1 161 - 448 None None 0
6BQLA 2.0 Active DFGin BLAminus in-in in-in BI9 Type1 161 - 448 None None 0
6BQPA 1.95 Active DFGin BLAminus in-in in-in 6T2 Type1 161 - 448 None None 0
6BQQA 1.8 Active DFGin BLAminus out-in in-in R78 Type1 161 - 448 None None 0
6BRCA 2.2 None DFGin BLAminus in-none in-in E5J Type1 161 - 448 None None 0
6BRCB 2.2 Active DFGin BLAminus in-in in-in E5J Type1 161 - 448 None None 0
8TUCA 1.5 Active DFGin BLAminus in-in in-in O7I Type1 161 - 449 None None 0
2ZV2A 2.4 Active DFGin BLAminus in-in in-in 609 Type1 160 - 448 None None 0
5YV8A 1.927 Active DFGin BLAminus in-in in-in 91L Type1 160 - 448 None None 0
5YVAA 2.574 Active DFGin BLAminus in-in in-in 91X Type1 160 - 448 None None 0
5YVBA 2.02 Active DFGin BLAminus in-in in-in 92C Type1 160 - 448 None None 0
5YVCA 2.02 Active DFGin BLAminus in-in in-in SU6 Type1 160 - 448 None None 0
5YV9A 2.53 Active DFGin BLAminus in-in in-in 91O Type1.5_Back 160 - 448 None None 0

CAMKK2 (Calcium/calmodulin-dependent protein kinase kinase 2)

Group: CAMK
Total number of chains: 20
Spatial Dihedral Chains Representative
DFGin BLAminus 20 AF-Q96RR4-K1A
Representatives from each cluster
Pymol session(ver 2.3) Pymol script
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment
Database table as tsv

Organism UniprotID PDB Resolution Activity Label Spatial Label Dihedral Label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Mutation Phosphorylation Unresolved residues in A-loop
Homo sapiens KKCC2_HUMAN AF-Q96RR4-K1A -1.0 Active DFGin BLAminus in-in in-in No_ligand No_ligand 157 - 454 None None 0
Homo sapiens KKCC2_HUMAN 6CMJA 2.4 Active DFGin BLAminus in-in in-in F6J Type1 161 - 463 None X345,X400,X462 0
Homo sapiens KKCC2_HUMAN 6CMJB 2.4 Active DFGin BLAminus in-in in-in F6J Type1 161 - 462 None X345,X400,X462 0
Homo sapiens KKCC2_HUMAN 5UY6A 1.7 Active DFGin BLAminus in-in in-in 8R4 Type1 161 - 448 None None 0
Homo sapiens KKCC2_HUMAN 5UYJA 1.6 Active DFGin BLAminus in-in in-in 8R7 Type1 161 - 449 None None 0
Homo sapiens KKCC2_HUMAN 5VT1A 1.9 Active DFGin BLAminus in-in in-in 9JS Type1 161 - 448 None None 0
Homo sapiens KKCC2_HUMAN 6BKUA 2.0 Active DFGin BLAminus in-in in-in DXV Type1 162 - 448 None None 0
Homo sapiens KKCC2_HUMAN 6BLEA 1.9 Active DFGin BLAminus in-in in-in 34U Type1 161 - 448 None None 0
Homo sapiens KKCC2_HUMAN 6BQLA 2.0 Active DFGin BLAminus in-in in-in BI9 Type1 161 - 448 None None 0
Homo sapiens KKCC2_HUMAN 6BQPA 1.95 Active DFGin BLAminus in-in in-in 6T2 Type1 161 - 448 None None 0
Homo sapiens KKCC2_HUMAN 6BQQA 1.8 Active DFGin BLAminus out-in in-in R78 Type1 161 - 448 None None 0
Homo sapiens KKCC2_HUMAN 6BRCA 2.2 None DFGin BLAminus in-none in-in E5J Type1 161 - 448 None None 0
Homo sapiens KKCC2_HUMAN 6BRCB 2.2 Active DFGin BLAminus in-in in-in E5J Type1 161 - 448 None None 0
Homo sapiens KKCC2_HUMAN 8TUCA 1.5 Active DFGin BLAminus in-in in-in O7I Type1 161 - 449 None None 0
Homo sapiens KKCC2_HUMAN 2ZV2A 2.4 Active DFGin BLAminus in-in in-in 609 Type1 160 - 448 None None 0
Homo sapiens KKCC2_HUMAN 5YV8A 1.927 Active DFGin BLAminus in-in in-in 91L Type1 160 - 448 None None 0
Homo sapiens KKCC2_HUMAN 5YVAA 2.574 Active DFGin BLAminus in-in in-in 91X Type1 160 - 448 None None 0
Homo sapiens KKCC2_HUMAN 5YVBA 2.02 Active DFGin BLAminus in-in in-in 92C Type1 160 - 448 None None 0
Homo sapiens KKCC2_HUMAN 5YVCA 2.02 Active DFGin BLAminus in-in in-in SU6 Type1 160 - 448 None None 0
Homo sapiens KKCC2_HUMAN 5YV9A 2.53 Active DFGin BLAminus in-in in-in 91O Type1.5_Back 160 - 448 None None 0

CAMKK2 (Calcium/calmodulin-dependent protein kinase kinase 2)

No non-human structures known.