6CCY

AKT1 (RAC-alpha serine/threonine-protein kinase)
Group: AGC
Uniprot: AKT1_HUMAN
Organism: Homo sapiens
Domain boundary: 150 - 408
Resolu: 2.18

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Active DFGin BLAminus in-in in-in EX4 Type1 144 - 983 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
       150        160        170        180 
GSLRVTMNEF EYLKLLGKGT FGKVILVKEK ATGRYYAMKI 
       190        200        210        220 
LKKEVIVAKD EVAHTLTESR VLQNSRHPFL TALKYSFQTH 
       230        240        250        260 
DRLCFVMEYA NGGELFFHLS RERVFSEDRA RFYGAEIVSA 
       270        280        290        300 
LDYLHSEKNV VYRDLKLENL MLDKDGHIKI TDFGLCKEGI 
       310        320        330        340 
KDGATMKTFC GTPEYLAPEV LEDNDYGRAV DWWGLGVVMY 
       350        360        370        380 
EMMCGRLPFY NQDHEKLFEL ILMEEIRFPR TLGPEAKSLL 
       390        400        410        420 
SGLLKKDPKQ RLGGGPSDAK EIMQHRFFAG IVWQHVYEKK 
       430        440        450        460 
LSPPFKPQVT SEVDTRYFDE EFTAQMITIT ppdqddsmec 
       972        982 
vdserreEQE MFRDFDYIAD WEG
Lower-case residues are disordered in structure.
Mutations: N199S,S396P,E397S,T433V
Phosphorylation: X308