5WFJ

JAK3 (Tyrosine-protein kinase JAK3)
Group: TYR
Uniprot: JAK3_HUMAN
Organism: Homo sapiens
Domain boundary: 822 - 1111
Resolu: 2.48

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Active DFGin BLAminus in-in in-in 9Z4 Type1 817 - 1099 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
       817        827        837        847 
gpasqdptiF EERHLKYISQ LGkgnfGSVE LCRYDPLGDN 
       857        867        877        887 
TGALVAVKQL QhsgPDQQRD FQREIQILKA LHSDFIVKYR 
       897        907        917        927 
GVSYGPgrqs LRLVMEYLPS GCLRDFLQRH RARLDASRLL 
       937        947        957        967 
LYSSQICKGM EYLGSRRCVH RDLAARNILV ESEAHVKIAD 
       977        987        997       1007 
FGLAKLLPLD KDYYVVrePG QSPIFWYAPE SLSDNIFSRQ 
      1017       1027       1037       1047 
SDVWSFGVVL YELFTYCDKS CSPSAEFLRM MgserdVPAL 
      1057       1067       1077       1087 
SRLLELLEEG QRLPAPPACP AEVHELMKLC WAPSPQDRPS 
      1097 
FSALGPQLDM LWs
Lower-case residues are disordered in structure.
Mutations: C811S,C1040S,C1048S
Phosphorylation: None