5WEV

JAK2 (Tyrosine-protein kinase JAK2)
Group: TYR
Uniprot: JAK2_HUMAN
Organism: Homo sapiens
Domain boundary: 849 - 1124
Resolu: 1.854

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Active DFGin BLAminus in-in in-in 9ZS Type1 833 - 1130 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
         -        833        843        853 
mgsshhhhhh ssglvprgsS GAFEDRDPTQ FEERHLKFLQ 
       863        873        883        893 
QLGKgnfGSV EMCRYDPLQD NTGEVVAVKK LQHSTEEHLR 
       903        913        923        933 
DFEREIEILK SLQHDNIVKY KGVCYSAGRR NLKLIMEYLP 
       943        953        963        973 
YGSLRDYLQK HKERIDHIKL LQYTSQICKG MEYLGTKRYI 
       983        993       1003       1013 
HRDLATRNIL VENENRVKIG DFGLTKVLPQ DKEYYKVKEP 
      1023       1033       1043       1053 
GESPIFWYAP ESLTESKFSV ASDVWSFGVV LYELFTYIEK 
      1063       1073       1083       1093 
SKSPPAEFMR MIGNDKQGQM IVFHLIELLK NNGRLPRPDG 
      1103       1113       1123 
CPDEIYMIMT ECWNNNVNQR PSFRDLALRV DQIRDNMag
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: X1007,X1008