5TX3

MELK (Maternal embryonic leucine zipper kinase)
Group: CAMK
Uniprot: MELK_HUMAN
Organism: Homo sapiens
Domain boundary: 11 - 263
Resolu: 2.9

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin ABAminus out-out none-out 7MY Type1 1 - 333 16
B Inactive None None out-out none-in 7MY Type1 1 - 334 19
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain B
         6         16         26         36 
gSGSMKDYDE LLKYYELHET IGtggfaKVK LACHILTGEM 
        46         56         66         76 
VAIKIMDKnt lgsdlpriKT EIEALKNLRH QHICQLYHVL 
        86         96        106        116 
ETANKIFMVL EYCPGGELFD YIISQDRLSE EETRVVFRQI 
       126        136        146        156 
VSAVAYVHSQ GYAHRDLKPE NLLFDEYHKL KLIDfglcak 
       166        176        186        196 
pkgnkdyhlq tccGSLAYAA PELIQGksyL GSEADVWSMG 
       206        216        226        236 
ILLYVLMCGF LPFDDDNVMA LYKKIMRGKY DVPKWLSPSS 
       246        256        266        276 
ILLLQQMLQV DPKKRISMKN LLNHPWIMQD YNYPVEWQSK 
       286        296        306        316 
NPFIHLDDDC VTELSVHHRN NRQTMEDLIS LWQYDHLTAT 
       326        336 
YLLLLAKKAR GKPVRLRLss fscg
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None