5TKD

TYK2 (Non-receptor tyrosine-protein kinase TYK2)
Pseudokinase
Group: TYR
Uniprot: TYK2_HUMAN
Organism: Homo sapiens
Domain boundary: 589 - 875
Resolu: 1.92

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin None in-none out-out 7GL Type1 581 - 866 0
B Inactive DFGin None in-none out-out 7GL Type1 581 - 867 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain B
       581        591        601        611 
ghmnlsqlsF HRVDQKEITQ LSHLGQGTRT NVYEGRLRve 
       621        631        641        651 
gsgdpeegkm ddedplvpgr drgqELRVVL KVLDPSHHDI 
       661        671        681        691 
ALAFYETASL MSQVSHTHLA FVHGVCVRGP ENIMVTEYVE 
       701        711        721        731 
HGPLDVWLRR ERGHVPMAWK MVVAQQLASA LSYLENKNLV 
       741        751        761        771 
HGNVCGRNIL LARLGLAegt SPFIKLSDPG VGLGALSREE 
       781        791        801        811 
RVERIPWLAP ECLPggansl STAMDKWGFG ATLLEICFDG 
       821        831        841        851 
EAPLqsRSPS EKEHFYQRQH RLPEPScpqL ATLTSQCLTY 
       861 
EPTQRPSFRT ILRDLTrl
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None