5TA6

PLK1 (Serine/threonine-protein kinase PLK1)
Group: CAMK
Uniprot: PLK1_HUMAN
Organism: Homo sapiens
Domain boundary: 53 - 305
Resolu: 2.5

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin BLAminus in-in in-out 79D Type1 37 - 330 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
         -          -         17         27 
msyyhhhhhh dydipttenl yfqgaapadp gkagvpgvaa 
        37         47         57         67 
pgapaaappA KEIPEVLVDP RSRRRYVRGR FLGKGGFAKC 
        77         87         97        107 
FEISDADTKE VFAGKIVPKS LLLKPHQREK MSMEISIHRS 
       117        127        137        147 
LAHQHVVGFH GFFEDNDFVF VVLELCRRRS LLELHKRRKA 
       157        167        177        187 
LTEPEARYYL RQIVLGCQYL HRNRVIHRDL KLGNLFLNED 
       197        207        217        227 
LEVKIGDFGL ATKVEYDGER KKVLCGTPNY IAPEVLSKKG 
       237        247        257        267 
HSFEVDVWSI GCIMYTLLVG KPPFETSCLK ETYLRIKKNE 
       277        287        297        307 
YSIPKHINPV AASLIQKMLQ TDPTARPTIN ELLNDEFFTS 
       317        327        337 
GYIPARLPIT CLTIPPRFSI APSsldpsnr kpltvlnk
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None