5OPV

CHEK1 (Serine/threonine-protein kinase Chk1)
Group: CAMK
Uniprot: CHK1_HUMAN
Organism: Homo sapiens
Domain boundary: 9 - 265
Resolu: 1.9

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Active DFGin BLAminus in-in in-in A3H Type1 3 - 270 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
        10         20         30         40 
maVPFVEDWD LVQTLGEGAY GEVQLAVNRV TEEAVAVKIV 
        50         60         70         80 
DMkravdcpE NIKKEICILK MLNHENVIKF YGHRREGNIQ 
        90        100        110        120 
YLFMELASGG SLFDRIEPDI GMPEPDAQRF FHQLMAGVVY 
       130        140        150        160 
LHGIGITHRD IKPHNLLLDE RDNLKIADYS LATVFRYNNR 
       170        180        190        200 
ERLLNKMCGT LPYVAPELLK RREFHAEPVD VWSCGIVLTA 
       210        220        230        240 
MLAGELPWDQ PSDSCQEYSD WKEKKTYLNP WKKIDSAPLA 
       250        260        270        280 
LLHKILVENP SARITIPDIK KDRWYNKPLK kgakrprvts 
         - 
ggvsespsgh hhhhhhh
Lower-case residues are disordered in structure.
Mutations: N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S
Phosphorylation: None