5HVY

CDK8 (Cyclin-dependent kinase 8)
Group: CMGC
Uniprot: CDK8_HUMAN
Organism: Homo sapiens
Domain boundary: 20 - 335
Resolu: 2.39

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGout BBAminus out-out out-out 66X Type2 1 - 359 12
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
         7         17         27         37 
dDKMDYDFKV KLSSERERVE DLFEYEGCKV GrgtyGHVYK 
        47         57         67         77 
AKRKDGKDDK DYALKQIEGT GISMSACREI ALLRELKHPN 
        87         97        107        117 
VISLQKVFLS HADRKVWLLF DYAEHDLWHI IKFHRASkan 
       127        137        147        157 
kkpVQLPRGM VKSLLYQILD GIHYLHANWV LHRDLKPANI 
       167        177        187        197 
LVMGEGPERG RVKIADMGFA RLfnsplkpl adldPVVVTF 
       207        217        227        237 
WYRAPELLLG ARHYTKAIDI WAIGCIFAEL LTSEPIFHCR 
       247        257        267        277 
qediKTSNPY HHDQLDRIFN VMGFPADKDW EDIKKMPEHS 
       287        297        307        317 
TLMKDFRRNT YTNCSLIKYM EKHKVKPDSK AFHLLQKLLT 
       327        337        347        357 
MDPIKRITSE QAMQDPYFLE DPLPTSDVFA GCQIPYPKRE 
       367        377        387        397 
FLteeepddk gdkknqqqqq gnnhtngtgh pgnqdsshtq 

gpplkk
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None