5HHW

INSR (Insulin receptor)
Group: TYR
Uniprot: INSR_HUMAN
Organism: Homo sapiens
Domain boundary: 1023 - 1292
Resolu: 1.79

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin None in-out out-in 60O Type1.5_Front 1005 - 1310 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
      1013       1023       1033       1043 
mVFPSSVYVP DEWEVSREKI TLLRELGQGS FGMVYEGNAR 
      1053       1063       1073       1083 
DIIKGEAETR VAVKTVNESA SLRERIEFLN EASVMKGFTC 
      1093       1103       1113       1123 
HHVVRLLGVV SKGQPTLVVM ELMAHGDLKS YLRSLRPEAE 
      1133       1143       1153       1163 
NNPGRPPPTL QEMIQMAAEI ADGMAYLNAK KFVHRNLAAR 
      1173       1183       1193       1203 
NCMVAHDFTV KIGDFGMTRD IYETDYYRKG GKGLLPVRWM 
      1213       1223       1233       1243 
APESLKDGVF TTSSDMWSFG VVLWEITSLA EQPYQGLSNE 
      1253       1263       1273       1283 
QVLKFVMDGG YLDQPDNCPE RVTDLMRMCW QFNPKMRPTF 
      1293       1303 
LEIVNLLKDD LHPSFPEVSF FHSEENK
Lower-case residues are disordered in structure.
Mutations: C1008S,D1159N
Phosphorylation: None