5FM3

RET (Proto-oncogene tyrosine-protein kinase receptor Ret)
Group: TYR
Uniprot: RET_HUMAN
Organism: Homo sapiens
Domain boundary: 724 - 1007
Resolu: 2.95

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Active DFGin BLAminus in-in in-in PP1 Type1 707 - 1011 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
       668        678        688        698 
cyhkfahkpp issaemtfrr paqafpvsys ssgarrpsld 
       708        718        728        738 
smenqvsvDA FKILEDPKWE FPRKNLVLGK TLGEGEFGKV 
       748        758        768        778 
VKATAFHLKG RAGYTTVAVK MLKENASPSE LRDLLSEFNV 
       788        798        808        818 
LKQVNHPHVI KLYGACSQDG PLLLIVEYAK YGSLRGFLRE 
       828        838        848        858 
Srkvgpgylg sggsrnsssl dhpderALTM GDLISFAWQI 
       868        878        888        898 
SQGMQYLAEM KLVHRDLAAR NILVAEGRKM KISDFGLSRD 
       908        918        928        938 
VYEEDSYVKR SQGRIPVKWM AIESLFDHIY TTQSDVWSFG 
       948        958        968        978 
VLLWEIVTLG GNPYPGIPPE RLFNLLKTGH RMERPDNCSE 
       988        998       1008 
EMYRLMLQCW KQEPDKRPVF ADISKDLEKM MVKrr
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: X809,X905,X909,X928