5EYM

MAP2K1 (Dual specificity mitogen-activated protein kinase kinase 1)
Group: STE
Uniprot: MP2K1_HUMAN
Organism: Homo sapiens
Domain boundary: 68 - 361
Resolu: 2.7

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin BLBplus out-out out-none 5U5 Type1 41 - 381 6
B Inactive DFGin BLBplus out-out out-none 5U5 Type1 41 - 381 6
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain B
        44         54         64         74 
kkleelELDE QQRKRLEAFL TQKQKVGELK DDDFEKISEL 
        84         94        104        114 
GAGnggVVFK VSHKPSGLVM ARKLIHLEIK PAIRNQIIRE 
       124        134        144        154 
LQVLHECNSP YIVGFYGAFY SDGEISICME HMDGGSLDQV 
       164        174        184        194 
LKKAGRIPEQ ILGKVSIAVI KGLTYLREkh kIMHRDVKPS 
       204        214        224        234 
NILVNSRGEI KLCDFGVSGQ LIDSMansfv gTRSYMSPER 
       244        254        264        274 
LqgthysVQS DIWSMGLSLV EMAVGRYPIP PPDAKELELM 
       284        294        304        314 
Fgcqvegdaa etpprprtpg rplnkfgmds rpPMAIFELL 
       324        334        344        354 
DYIVNEPPPK LPSGVFSLEF QDFVNKCLIK NPAERADLKQ 
       364        374        384 
LMVHAFIKRS DAEEVDFAGW LCSTIGLnqp stpthaagv
Lower-case residues are disordered in structure.
Mutations: S298N,S299K,Y300F
Phosphorylation: None