5E8V

TGFBR2 (TGF-beta receptor type-2)
Group: TKL
Uniprot: TGFR2_HUMAN
Organism: Homo sapiens
Domain boundary: 244 - 540
Resolu: 1.69

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Active DFGin BLAminus in-in in-in No_ligand No_ligand 240 - 541 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
       243        253        263        273 
ghmhntELLP IELDTLVGKG RFAEVYKAKL KqntseqFET 
       283        293        303        313 
VAVKIFPYEE YASWKTEKDI FSDINLKHEN ILQFLTAEER 
       323        333        343        353 
KTELGKQYWL ITAFHAKGNL QEYLTRHVIS WEDLRKLGSS 
       363        373        383        393 
LARGIAHLHS DHTPCGRPKM PIVHRDLKSS NILVKNDLTC 
       403        413        423        433 
CLCDFGLSLR LDPTLSVDDL ANSGQVGTAR YMAPEVLASA 
       443        453        463        473 
MNLENVESFK QTDVYSMALV LWEMTSRCNA VGEVKDYEPP 
       483        493        503        513 
FGSKVREHPC VASMADNVLA DAGRPEIPSF WLNHQGIQMV 
       523        533        543 
CETLTECWDH DPEARLTAQC VAERFSELeh ldrlsg
Lower-case residues are disordered in structure.
Mutations: E431A,R433A,E485A,K488A,R493A,R495A
Phosphorylation: None