5DEY

PAK1 (Serine/threonine-protein kinase PAK 1)
Group: STE
Uniprot: PAK1_HUMAN
Organism: Homo sapiens
Domain boundary: 270 - 521
Resolu: 2.1

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin BLAminus out-out in-in 59T Type1.5_Back 250 - 544 0
B Inactive DFGin None out-out none-out 59T Type1 255 - 542 7
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain B
       258        268        278        288 
sdeeilEKLR SIVSVGDPKK KYTRFEKIGQ GASGTVYTAM 
       298        308        318        328 
DVATGQEVAI KQMNLQQQPK KELIINEILV MRENKNPNIV 
       338        348        358        368 
NYLDSYLVGD ELWVVMEYLA GGSLTDVVTE TCMDEGQIAA 
       378        388        398        408 
VCRECLQALE FLHSNQVIHR NIKSDNILLG MDGSVKLTDF 
       418        428        438        448 
GFcaqitpeQ SKRSEMVGTP YWMAPEVVTR KAYGPKVDIW 
       458        468        478        488 
SLGIMAIEMI EGEPPYLNEN PLRALYLIAT NGTPELQNPE 
       498        508        518        528 
KLSAIFRDFL NRCLEMDVEK RGSAKELLQH QFLKIAKPLS 
       538 
SLTPLIAAAK EATKnnh
Lower-case residues are disordered in structure.
Mutations: D389N,T423E
Phosphorylation: None