5C03

TYK2 (Non-receptor tyrosine-protein kinase TYK2)
Pseudokinase
Group: TYR
Uniprot: TYK2_HUMAN
Organism: Homo sapiens
Domain boundary: 589 - 875
Resolu: 1.9

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin None in-none out-out AGS Type1 579 - 869 0
B Inactive DFGin None in-none out-out AGS Type1 580 - 870 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain B
         -          -        559        569 
msyyhhhhhh dydipttenl yfqgamgets nliimrgara 
       579        589        599        609 
sprtlnlsql SFHRVDQKEI TQLSHLGQGT RTNVYEGRLR 
       619        629        639        649 
vegsgdpeeg kmddedplvp grdrgqELRV VLKVLDPSHH 
       659        669        679        689 
DIALAFYETA SLMSQVSHTH LAFVHGVCVR GPENIMVTEY 
       699        709        719        729 
VEHGPLDVWL RRERGHVPMA WKMVVAQQLA SALSYLENKN 
       739        749        759        769 
LVHGNVCGRN ILLARLGLAE GTSPFIKLSD PGVGLGALSR 
       779        789        799        809 
EERVERIPWL APECLPggan sLSTAMDKWG FGATLLEICF 
       819        829        839        849 
DGEAPLQSRS PSEKEHFYQR QHRLPEPSCP QLATLTSQCL 
       859        869 
TYEPTQRPSF RTILRDLTRL Qp
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None