4YTI

JAK2 (Tyrosine-protein kinase JAK2)
Group: TYR
Uniprot: JAK2_HUMAN
Organism: Homo sapiens
Domain boundary: 849 - 1124
Resolu: 2.52

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Active DFGin BLAminus in-in in-in VJK Type1 842 - 1130 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
       846        856        866        876 
gshnmTQFEE RHLKFLQQLG KGNFGSVEMC RYDPLQDNTG 
       886        896        906        916 
EVVAVKKLQH STEEHLRDFE REIEILKSLQ HDNIVKYKGV 
       926        936        946        956 
CYSagrRNLK LIMEYLPYGS LRDYLQKHKE RIDHIKLLQY 
       966        976        986        996 
TSQICKGMEY LGTKRYIHRD LATRNILVEN ENRVKIGDFG 
      1006       1016       1026       1036 
LTKVLPQDKE YYKVKEPGES PIFWYAPESL TESKFSVASD 
      1046       1056       1066       1076 
VWSFGVVLYE LFTYIEKSKS PPAEFMRMIG NDKQGQMIVF 
      1086       1096       1106       1116 
HLIELLKNNG RLPRPDGCPD EIYMIMTECW NNNVNQRPSF 
      1126 
RDLALRVDQI RDNMag
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: X1007,X1008