4YHF

BTK (Tyrosine-protein kinase BTK)
Group: TYR
Uniprot: BTK_HUMAN
Organism: Homo sapiens
Domain boundary: 402 - 653
Resolu: 2.2

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin BLBplus out-none out-out 4C9 Type1.5_Back 391 - 658 0
B Inactive DFGin BLBplus out-out out-out 4C9 Type1.5_Back 390 - 658 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain B
       391        401        411        421 
knapstagLG YGSWEIDPKD LTFLKELGTG QFGVVKYGKW 
       431        441        451        461 
RGQYDVAIKM IKEGSMSEDE FIEEAKVMMN LSHEKLVQLY 
       471        481        491        501 
GVCTKQRPIF IITEYMANGC LLNYLREMRH RFQTQQLLEM 
       511        521        531        541 
CKDVCEAMEY LESKQFLHRD LAARNCLVND QGVVKVSDFG 
       551        561        571        581 
LSRYVLDDEY TSSVGSKFPV RWSPPEVLMY SKFSSKSDIW 
       591        601        611        621 
AFGVLMWEIY SLGKMPYERF TNSETAEHIA QGLRLYRPHL 
       631        641        651 
ASEKVYTIMY SCWHEKADER PTFKILLSNI LDVMDEEs
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None