4Y93

BTK (Tyrosine-protein kinase)
Group: TYR
Uniprot: Q3ZC95_BOVIN
Organism: Bos taurus
Domain boundary: 402 - 653
Resolu: 1.695

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin BLBplus out-out out-out 746 Type1 1 - 658 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
         9         19         29         39 
GMATVILESI FLKRSqqkkk tspLNFKKRL FLLTVQKLSY 
        49         59         69         79 
YEYDFERGRR GSKKGSIDVE KITCVETVVP EKNPPPERQI 
        89         99        109        119 
Prrgeesset EQISIIERFP YPFQVVYDEG PLYVFSPTEE 
       129        139        149        159 
LRKRWIHQLK NVIRYNSDLV QKYHPCFWID GQYLCCSQTA 
         -        392        402        412 
KNAMGCQILA AAPSTAGLGY GSWEIDPKDL TFLKELGTGQ 
       422        432        442        452 
FGVVKYGKWR GQYDVAIKMI KEGSMSEDEF IEEAKVMMNL 
       462        472        482        492 
SHEKLVQLYG VCTKQRPIFI ITEYMANGCL LNYLREMRHR 
       502        512        522        532 
FQTQQLLEMC KDVCEAMEYL ESKQFLHRDL AARNCLVNDQ 
       542        552        562        572 
GVVKVSDFGM TRYVLDDEYT SSTGSKFPVK WASPEVLMYS 
       582        592        602        612 
KFSSKSDIWA FGVLMWEIYS LGKMPYERFT NSETAEHIAQ 
       622        632        642        652 
GLRLPRPHLA SERVYAIMYS CWHEKADERP TFKILLSNIL 

DVMDEE
Lower-case residues are disordered in structure.
Mutations: L542M,S543T,V555T,R562K,S564A,P565S,Y617P
Phosphorylation: None