4L01

JAK1 (Tyrosine-protein kinase JAK1)
Pseudokinase
Group: TYR
Uniprot: JAK1_HUMAN
Organism: Homo sapiens
Domain boundary: 583 - 855
Resolu: 1.9

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin None in-none out-out No_ligand No_ligand 565 - 850 0
B Inactive DFGin None in-none out-out No_ligand No_ligand 565 - 849 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain B
       566        576        586        596 
gstsaqewQP VYPMSQLSFD RILKKDLVQG EHLGRGTRTH 
       606        616        626        636 
IYSGTLMDyk ddegtseeKK IKVILKVLDP SHRDISLAFF 
       646        656        666        676 
EAASMMRQVS HKHIVYLYGV CFRdVENIMV EEFVEGGPLD 
       686        696        706        716 
LFMHRKSDVL TTPWKFKVAK QLASALSYLE DKDLVHGNVC 
       726        736        746        756 
TKNLLLAREG IDSECGPFIK LSDPGIPITV LSRQECIERI 
       766        776        786        796 
PWIAPECVED SKNLSVAADK WSFGTTLWEI CYNGEIPLKD 
       806        816        826        836 
KTLIEKERFY ESRCRPVTPS CKELADLMTR CMNYDPNQRP 
       846        856 
FFRAIMRDIN KLEeqnpdiv sekk
Lower-case residues are disordered in structure.
Mutations: V658F
Phosphorylation: None