4J7B

PLK1 (Serine/threonine-protein kinase PLK)
Group: CAMK
Uniprot: Q6DRK7_DANRE
Organism: Danio rerio
Domain boundary: 39 - 291
Resolu: 2.3

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin BLAminus in-in in-out No_ligand No_ligand 18 - 311 10
D Inactive DFGin ABAminus out-in in-out No_ligand No_ligand 20 - 311 11
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain D
        25         35         45         55 
mgpkSAPLKE IPDVLVDPRT MKRYMRGRFL GKGGFAKCYE 
        65         75         85         95 
ITDMDTKEVF AGKVVPKSML LKPHQKEKMS TEIAIHKSLD 
       105        115        125        135 
NPHVVGFHGF FEDDDFVYVV LEICRRRSLL ELHKRRKAVT 
       145        155        165        175 
EPEARYFMRQ TIQGVQYLHN NRVIHRNLKL GNLFLNDDMD 
       185        195        205        215 
VKIGDFGLAT KIefdgfrkk tlcGTPNYIA PEVLCKKGHS 
       225        235        245        255 
FEVDIWSLGC ILYTLLVGKP PFETSCLKET YIRIKKNEYS 
       265        275        285        295 
VPRHINPVAS ALIRRMLHAD PTLRPSVAEL LTDEFFTSGY 
       305 
APMRLPTSCL TVPPRFs
Lower-case residues are disordered in structure.
Mutations: D162N,E192F
Phosphorylation: None