4J52

PLK1 (Serine/threonine-protein kinase PLK1)
Group: CAMK
Uniprot: PLK1_HUMAN
Organism: Homo sapiens
Domain boundary: 53 - 305
Resolu: 2.3

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin BLAminus in-in in-out 1J3 Type1 38 - 330 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
        47         57         67         77 
KEIPEVLVDP RSRRRYVRGR FLGKGGFAKC FEISDADTKE 
        87         97        107        117 
VFAGKIVPKS LLLKPHQREK MSMEISIHRS LAHQHVVGFH 
       127        137        147        157 
GFFEDNDFVF VVLELCRRRS LLELHKRRKA LTEPEARYYL 
       167        177        187        197 
RQIVLGCQYL HRNRVIHRDL KLGNLFLNED LEVKIGDFGL 
       207        217        227        237 
ATKVEYDGER KKVLCGTPNY IAPEVLSKKG HSFEVDVWSI 
       247        257        267        277 
GCIMYTLLVG KPPFETSCLK ETYLRIKKNE YSIPKHINPV 
       287        297        307        317 
AASLIQKMLQ TDPTARPTIN ELLNDEFFTS GYIPARLPIT 
       327 
CLTIPPRFSI APS
Lower-case residues are disordered in structure.
Mutations: T210V
Phosphorylation: None