4I6Q

JAK3 (Tyrosine-protein kinase JAK3)
Group: TYR
Uniprot: JAK3_HUMAN
Organism: Homo sapiens
Domain boundary: 822 - 1111
Resolu: 1.85

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Active DFGin BLAminus in-in in-in 1DT Type1 815 - 1102 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
       820        830        840        850 
cqdpTIFEER HLKYISQLGK GNFGSVELCR YDPLGDNTGA 
       860        870        880        890 
LVAVKQLQHS GPDQQRDFQR EIQILKALHS DFIVKYRGVS 
       900        910        920        930 
YgpgrqsLRL VMEYLPSGCL RDFLQRHRAR LDASRLLLYS 
       940        950        960        970 
SQICKGMEYL GSRRCVHRDL AARNILVESE AHVKIADFGL 
       980        990       1000       1010 
AKLLPLDKDY YVVREPGQSP IFWYAPESLS DNIFSRQSDV 
      1020       1030       1040       1050 
WSFGVVLYEL FTYCDKSCSP SAEFLRMMgs erdVPALSRL 
      1060       1070       1080       1090 
LELLEEGQRL PAPPACPAEV HELMKLCWAP SPQDRPSFSA 
      1100       1110       1120 
LGPQLDMLWS GSrgcethaf tahpegkhhs lsfs
Lower-case residues are disordered in structure.
Mutations: C1040S,C1048S
Phosphorylation: None