4E20

TYK2 (Non-receptor tyrosine-protein kinase TYK2)
Group: TYR
Uniprot: TYK2_MOUSE
Organism: Mus musculus
Domain boundary: 894 - 1166
Resolu: 2.6

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin ABAminus in-in in-in 0MY Type1 885 - 1174 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
       894        904        914        924 
DPTVFHKRYL KKIRDLGEGH FGKVSLYCYD PTNDGTGEMV 
       934        944        954        964 
AVKALKEGCG PQLRSGWQRE IEILRTLYHE HIVKYKGCCE 
       974        984        994       1004 
DqgekSVQLV MEYVPLGSLR DYLPRHCVGL AQLLLFAQQI 
      1014       1024       1034       1044 
CEGMAYLHAQ HYIHRALAAR NVLLDNDRLV KIGDFGLAKA 
      1054       1064       1074       1084 
VPEGHEYYRV REDGDSPVFW YAPECLKECK FYYASDVWSF 
      1094       1104       1114       1124 
GVTLYELLTY CDSNQSPHTK FTELIGhtqg QMTVLRLTEL 
      1134       1144       1154       1164 
LERGERLPRP DRCPCEIYHL MKNCWETEAS FRPTFQNLVP 
      1174 
ILQTAQEKYQ
Lower-case residues are disordered in structure.
Mutations: D1020A
Phosphorylation: None