4E1Z

TYK2 (Non-receptor tyrosine-protein kinase TYK2)
Group: TYR
Uniprot: TYK2_MOUSE
Organism: Mus musculus
Domain boundary: 894 - 1166
Resolu: 2.5

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin ABAminus in-in in-in 0MX Type1 884 - 1174 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
       893        903        913        923 
SDPTVFHKRY LKKIRDLGEG HFGKVSLYCY DPTNDGTGEM 
       933        943        953        963 
VAVKALKEGC GPQLRSGWQR EIEILRTLYH EHIVKYKGCC 
       973        983        993       1003 
EDqgeKSVQL VMEYVPLGSL RDYLPRHCVG LAQLLLFAQQ 
      1013       1023       1033       1043 
ICEGMAYLHA QHYIHRALAA RNVLLDNDRL VKIGDFGLAK 
      1053       1063       1073       1083 
AVPEGHEYYR VREDGDSPVF WYAPECLKEC KFYYASDVWS 
      1093       1103       1113       1123 
FGVTLYELLT YCDSNQSPHT KFTELIGHTQ GQMTVLRLTE 
      1133       1143       1153       1163 
LLERGERLPR PDRCPCEIYH LMKNCWETEA SFRPTFQNLV 
      1173 
PILQTAQEKY Q
Lower-case residues are disordered in structure.
Mutations: D1020A
Phosphorylation: None