4D2R

IGF1R (Insulin-like growth factor 1 receptor)
Group: TYR
Uniprot: IGF1R_HUMAN
Organism: Homo sapiens
Domain boundary: 999 - 1268
Resolu: 2.1

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin None out-out out-in DYK Type1 985 - 1286 2
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
       994       1004       1014       1024 
DVYVPDEWEV AREKITMSRE LGQGSFGMVY EGVAKGVVKD 
      1034       1044       1054       1064 
EPETRVAIKT VNEAASMRER IEFLNEASVM KEFNCHHVVR 
      1074       1084       1094       1104 
LLGVVSQGQP TLVIMELMTR GDLKSYLRSL RPEMENNPVL 
      1114       1124       1134       1144 
APPSLSKMIQ MAGEIADGMA YLNANKFVHR DLAARNCMVA 
      1154       1164       1174       1184 
EDFTVKIGDF GMTRDIYETD YYRKggKGLL PVRWMSPESL 
      1194       1204       1214       1224 
KDGVFTTYSD VWSFGVVLWE IATLAEQPYQ GLSNEQVLRF 
      1234       1244       1254       1264 
VMEGGLLDKP DNCPDMLFEL MRMCWQYNPK MRPSFLEIIS 
      1274       1284 
SIKEEMEPGF REVSFYYSEE NK
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None