4C3F

LCK (Tyrosine-protein kinase Lck)
Group: TYR
Uniprot: LCK_HUMAN
Organism: Homo sapiens
Domain boundary: 245 - 496
Resolu: 1.72

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin BLBplus in-in out-out 7KW Type1 238 - 498 4
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
       244        254        264        274 
gpeWEVPRET LKLVERLGAG QFGEVWMGYY NGHTKVAVKS 
       284        294        304        314 
LKQGSMSPDA FLAEANLMKQ LQHQRLVRLY AVVTQEPIYI 
       324        334        344        354 
ITEYMENGSL VDFLKTPSGI KLTINKLLDM AAQIAEGMAF 
       364        374        384        394 
IEERNYIHRN LRAANILVSD TLSCKIADFG LARLIEDNEY 
       404        414        424        434 
TARegakFPI KWTAPEAINY GTFTIKSDVW SFGILLTEIV 
       444        454        464        474 
THGRIPYPGM TNPEVIQNLE RGYRMVRPDN CPEELYQLMR 
       484        494 
LCWKERPEDR PTFDYLRSVL EDFFtat
Lower-case residues are disordered in structure.
Mutations: D364N
Phosphorylation: None