4AGU

CDKL1 (Cyclin-dependent kinase-like 1)
Group: CMGC
Uniprot: CDKL1_HUMAN
Organism: Homo sapiens
Domain boundary: 5 - 288
Resolu: 2.4

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A None DFGin BLAminus in-in in-none D15 Type1 2 - 291 12
B None DFGin BLAminus in-in in-none D15 Type1 3 - 292 12
C None DFGin BLAminus in-in in-none D15 Type1 2 - 291 12
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain C
         9         19         29         39 
mmEKYEKIGK IGEGSYGVVF KCRNRDTGQI VAIKKFLESE 
        49         59         69         79 
DDPVIKKIAL REIRMLKQLK HPNLVNLLEV FRRKRRLHLV 
        89         99        109        119 
FEYCDHTVLH ELDRYQRGVP EHLVKSITWQ TLQAVNFCHK 
       129        139        149        159 
HNCIHRDVKP ENILITKHSV IKLCDFGFAR LLtgpsdyyd 
       169        179        189        199 
devaTRWYRS PELLVGDTQY GPPVDVWAIG CVFAELLSGV 
       209        219        229        239 
PLWPGKSDVD QLYLIRKTLG DLIPRHQQVF STNQYFSGVK 
       249        259        269        279 
IPDPEDMEPL ELKFPNISYP ALGLLKGCLH MDPTERLTCE 
       289        299          - 
QLLHHPYFEN IReiedlake hdkpaenlyf q
Lower-case residues are disordered in structure.
Mutations: T159D,Y161E
Phosphorylation: None