3ZON

TYK2 (Non-receptor tyrosine-protein kinase TYK2)
Pseudokinase
Group: TYR
Uniprot: TYK2_HUMAN
Organism: Homo sapiens
Domain boundary: 589 - 875
Resolu: 2.15

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin None in-none out-out IK1 Type1 577 - 870 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
       548        558        568        578 
smgddcfslr rcclpqpget snliimrgar asprtlnlSQ 
       588        598        608        618 
LSFHRVDQKE ITQLSHLGQG TRTNVYEGRL RVegsgdpee 
       628        638        648        658 
gkmddedplv pgrdrgqELR VVLKVLDPSH HDIALAFYET 
       668        678        688        698 
ASLMSQVSHT HLAFVHGVCV RGPENIMVTE YVEHGPLDVW 
       708        718        728        738 
LRRERGHVPM AWKMVVAQQL ASALSYLENK NLVHGNVCGR 
       748        758        768        778 
NILLARLGLA EGTSPFIKLS DPGVGLGALS REERVERIPW 
       788        798        808        818 
LAPECLPgga nsLSTAMDKW GFGATLLEIC FDGEAPLQSR 
       828        838        848        858 
SPSEKEHFYQ RQHRLPEPsc pQLATLTSQC LTYEPTQRPS 
       868 
FRTILRDLTR LQphn
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None