3ZBF

ROS1 (Proto-oncogene tyrosine-protein kinase ROS)
Group: TYR
Uniprot: ROS1_HUMAN
Organism: Homo sapiens
Domain boundary: 1945 - 2217
Resolu: 2.2

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin ABAminus in-in in-out VGH Type1 1934 - 2230 12
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
         -          -       1940       1950 
mahhhhhhdy gipttenlyf qgsIENLPAF PREKLTLRLL 
      1960       1970       1980       1990 
LGSgafGEVY EGTAVDILGV GSGEIKVAVK TLKKGSTDQE 
      2000       2010       2020       2030 
KIEFLKEAHL MSKFNHPNIL KQLGVCLLNE PQYIILELME 
      2040       2050       2060       2070 
GGDLLTYLRK ARMATFYGPL LTLVDLVDLC VDISKGCVYL 
      2080       2090       2100       2110 
ERMHFIHRDL AARNCLVSVK DYTSPRIVKI GDFGLARDIY 
      2120       2130       2140       2150 
kndyyrkrge glLPVRWMAP ESLMDGIFTT QSDVWSFGIL 
      2160       2170       2180       2190 
IWEILTLGHQ PYPAHSNLDV LNYVQTGGRL EPPRNCPDDL 
      2200       2210       2220       2230 
WNLMTQCWAQ EPDQRPTFHR IQDQLQLFRN FFLNSIYKSR 

de
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None