3T9T

ITK (Tyrosine-protein kinase ITK/TSK)
Group: TYR
Uniprot: ITK_HUMAN
Organism: Homo sapiens
Domain boundary: 363 - 614
Resolu: 1.65

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin BLBplus out-out out-out IAQ Type1 356 - 618 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
       363        373        383        393 
gkWVIDPSEL TFVQEIGSGQ FGLVHLGYWL NKDKVAIKTI 
       403        413        423        433 
REGAMSEEDF IEEAEVMMKL SHPKLVQLYG VCLEQAPICL 
       443        453        463        473 
VTEFMEHGCL SDYLRTQRGL FAAETLLGMC LDVCEGMAYL 
       483        493        503        513 
EEACVIHRDL AARNCLVGEN QVIKVSDFGM TRFVLDDQYT 
       523        533        543        553 
SSTGTKFPVK WASPEVFSFS RYSSKSDVWS FGVLMWEVFS 
       563        573        583        593 
EGKIPYENRS NSEVVEDIST GFRLYKPRLA STHVYQIMNH 
       603        613 
CWRERPEDRP AFSRLLRQLA EIAESgl
Lower-case residues are disordered in structure.
Mutations: F435T,K596R
Phosphorylation: None