3O23

IGF1R (Insulin-like growth factor 1 receptor)
Group: TYR
Uniprot: IGF1R_HUMAN
Organism: Homo sapiens
Domain boundary: 999 - 1268
Resolu: 2.1

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGout None out-out out-in MQY Type2 991 - 1283 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
       991       1001       1011       1021 
saadvfvpdE WEVAREKITM SRELGQGSFG MVYEGVAKGV 
      1031       1041       1051       1061 
VKDEPETRVA IKTVNEAASM RERIEFLNEA SVMKEFNCHH 
      1071       1081       1091       1101 
VVRLLGVVSQ GQPTLVIMEL MTRGDLKSYL RSLRPEMENN 
      1111       1121       1131       1141 
PVLAPPSLSK MIQMAGEIAD GMAYLNANKF VHRDLAARNC 
      1151       1161       1171       1181 
MVAEDFTVKI GDFGMTRDIY ETDYYRKGGK GLLPVRWMSP 
      1191       1201       1211       1221 
ESLKDGVFTT YSDVWSFGVV LWEIATLAEQ PYQGLSNEQV 
      1231       1241       1251       1261 
LRFVMEGGLL DKPDNCPDML FELMRMCWQY NPKMRPSFLE 
      1271       1281 
IISSIKEEME PGFREVSFYY SEenk
Lower-case residues are disordered in structure.
Mutations: Y987F
Phosphorylation: None