3LXK

JAK3 (Tyrosine-protein kinase JAK3)
Group: TYR
Uniprot: JAK3_HUMAN
Organism: Homo sapiens
Domain boundary: 822 - 1111
Resolu: 2.0

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin ABAminus in-in in-in MI1 Type1 815 - 1098 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
       807        817        827        837 
mghhhhhhaq lyacqdpTIF EERHLKYISQ LGKGNFGSVE 
       847        857        867        877 
LCRYDPLGDN TGALVAVKQL QHSGPDQQRD FQREIQILKA 
       887        897        907        917 
LHSDFIVKYR GVSYGPGRQS LRLVMEYLPS GCLRDFLQRH 
       927        937        947        957 
RARLDASRLL LYSSQICKGM EYLGSRRCVH RDLAARNILV 
       967        977        987        997 
ESEAHVKIAD FGLAKLLPLD KDYYVVREPG QSPIFWYAPE 
      1007       1017       1027       1037 
SLSDNIFSRQ SDVWSFGVVL YELFTYCDKS CSPSAEFLRM 
      1047       1057       1067       1077 
MgcerdVPAL SRLLELLEEG QRLPAPPACP AEVHELMKLC 
      1087       1097       1107       1117 
WAPSPQDRPS FSALGPQLDM Lwsgsrgcet haftahpegk 

hhslsfs
Lower-case residues are disordered in structure.
Mutations: C1048S
Phosphorylation: None