3JY9

JAK2 (Tyrosine-protein kinase JAK2)
Group: TYR
Uniprot: JAK2_HUMAN
Organism: Homo sapiens
Domain boundary: 849 - 1124
Resolu: 2.1

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Active DFGin BLAminus in-in in-in JZH Type1.5_Back 842 - 1130 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
         -          -        849        859 
mgsshhhhhh ssglvprgsh nmTQFEERHL KFLQQLGKGn 
       869        879        889        899 
fGSVEMCRYD PLQDNTGEVV AVKKLQHSTE EHLRDFEREI 
       909        919        929        939 
EILKSLQHDN IVKYKGVCYS agrRNLKLIM EYLPYGSLRD 
       949        959        969        979 
YLQKHKERID HIKLLQYTSQ ICKGMEYLGT KRYIHRDLAT 
       989        999       1009       1019 
RNILVENENR VKIGDFGLTK VLPQDKEYYK VKEPGESPIF 
      1029       1039       1049       1059 
WYAPESLTES KFSVASDVWS FGVVLYELFT YIEKSKSPPA 
      1069       1079       1089       1099 
EFMRMIGNDK QGQMIVFHLI ELLKNNGRLP RPDGCPDEIY 
      1109       1119       1129 
MIMTECWNNN VNQRPSFRDL ALRVDQIRDN M
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: X1007,X1008