3G33

CDK4 (Cyclin-dependent kinase 4)
Group: CMGC
Uniprot: CDK4_HUMAN
Organism: Homo sapiens
Domain boundary: 6 - 295
Resolu: 3.0

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive DFGin BLAplus out-out out-out No_ligand No_ligand 5 - 295 0
C Inactive DFGin BLAplus out-out out-out No_ligand No_ligand 5 - 295 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain C
         5         15         25         35 
gplgsmatsR YEPVAEIGVG AYGTVYKARD PHSGHFVALK 
        45         55         65         75 
SVRVPNGGGG GGGLPISTVR EVALLRRLEA FEHPNVVRLM 
        85         95        105        115 
DVCATSRTDR EIKVTLVFEH VDQDLRTYLD KAPPPGLPAE 
       125        135        145        155 
TIKDLMRQFL RGLDFLHANC IVHRDLKPEN ILVTSGGTVK 
       165        175        185        195 
LADFGLARIY SYQMALTPVV VTLWYRAPEV LLQSTYATPV 
       205        215        225        235 
DMWSVGCIFA EMFRRKPLFC GNSEADQLGK IFDLIGLPPE 
       245        255        265        275 
DDWPRDVSLP RGAFPPRGPR PVQSVVPEME ESGAQLLLEM 
       285        295 
LTFNPHKRIS AFRALQHSYL hkdegnpe
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None