3FME

MAP2K6 (Dual specificity mitogen-activated protein kinase kinase 6)
Group: STE
Uniprot: MP2K6_HUMAN
Organism: Homo sapiens
Domain boundary: 53 - 314
Resolu: 2.26

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Inactive None None out-out none-out STU Type1 47 - 333 15
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
        54         64         74         84 
sMEVKADDLE PIMELGRGAY GVVEKMRHVP SGQIMAVKRI 
        94        104        114        124 
RatvNSQEQK RLLMDLDISM RTVDCPFTVT FYGALFREGD 
       134        144        154        164 
VWICMELMDT SLDKFYKQVI DKGQTIPEDI LGKIAVSIVK 
       174        184        194        204 
ALEHLHSKLS VIHRDVKPSN VLINALGQVK MCDFgisgyl 
       214        224        234        244 
vddvakdidA GCKPYMAPER INPELNQkgY SVKSDIWSLG 
       254        264        274        284 
ITMIELAILR FPYDSWGTPF QQLKQVVEEP SPQLPADKFS 
       294        304        314        324 
AEFVDFTSQC LKKNSKERPT YPELMQHPFF TLHESKGTDV 
       334 
ASFVKLILGd
Lower-case residues are disordered in structure.
Mutations: S207D,T211D
Phosphorylation: None