2ZOQ

MAPK3 (Mitogen-activated protein kinase 3)
Group: CMGC
Uniprot: MK03_HUMAN
Organism: Homo sapiens
Domain boundary: 42 - 330
Resolu: 2.39

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Active DFGin BLAminus in-in in-in 5ID Type1 24 - 375 0
B Inactive DFGin BLAminus in-out in-in 5ID Type1 24 - 375 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain B
         7         17         27         37 
lgsmaaaaaq gggggeprrt egvgpgVPGE VEMVKGQPFD 
        47         57         67         77 
VGPRYTQLQY IGEGAYGMVS SAYDHVRKTR VAIKKISPFE 
        87         97        107        117 
HQTYCQRTLR EIQILLRFRH ENVIGIRDIL RASTLEAMRD 
       127        137        147        157 
VYIVQDLMET DLYKLLKSQQ LSNDHICYFL YQILRGLKYI 
       167        177        187        197 
HSANVLHRDL KPSNLLINTT CDLKICDFGL ARIADPEHDH 
       207        217        227        237 
TGFLTEYVAT RWYRAPEIML NSKGYTKSID IWSVGCILAE 
       247        257        267        277 
MLSNRPIFPG KHYLDQLNHI LGILGSPSQE DLNCIINMKA 
       287        297        307        317 
RNYLQSLPSK TKVAWAKLFP KSDSKALDLL DRMLTFNPNK 
       327        337        347        357 
RITVEEALAH PYLEQYYDPT DEPVAEEPFT FAMELDDLPK 
       367        377 
ERLKELIFQE TARFQPGVle ap
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: X204