2X7O

TGFBR1 (TGF-beta receptor type-1)
Group: TKL
Uniprot: TGFR1_HUMAN
Organism: Homo sapiens
Domain boundary: 205 - 494
Resolu: 3.7

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Active DFGin BLAminus in-in in-in ZOP Type1 171 - 500 0
B Inactive DFGin BLAminus in-out in-in ZOP Type1 171 - 500 0
C Active DFGin BLAminus in-in in-in ZOP Type1.5_Back 171 - 500 0
D Active DFGin BLAminus in-in in-in ZOP Type1.5_Back 171 - 500 0
E Active DFGin BLAminus in-in in-in ZOP Type1.5_Back 171 - 500 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain E
       171        181        191        201 
edpsldrpfI SEGTTLKDLI YDMTTSGSGS GLPLLVQRTI 
       211        221        231        241 
ARTIVLQESI GKGRFGEVWR GKWRGEEVAV KIFSSREERS 
       251        261        271        281 
WFREAEIYQT VMLRHENILG FIAADNKDNG TWTQLWLVSD 
       291        301        311        321 
YHEHGSLFDY LNRYTVTVEG MIKLALSTAS GLAHLHMEIV 
       331        341        351        361 
GTQGKPAIAH RDLKSKNILV KKNGTCCIAD LGLAVRHDSA 
       371        381        391        401 
TDTIDIAPNH RVGTKRYMAP EVLDDSINMK HFESFKRADI 
       411        421        431        441 
YAMGLVFWEI ARRCSIGGIH EDYQLPYYDL VPSDPSVEEM 
       451        461        471        481 
RKVVCEQKLR PNIPNRWQSC EALRVMAKIM RECWYANGAA 
       491        501 
RLTALRIKKT LSQLSQQEGi km
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: None