2X4Z

PAK4 (Serine/threonine-protein kinase PAK 4)
Group: STE
Uniprot: PAK4_HUMAN
Organism: Homo sapiens
Domain boundary: 321 - 572
Resolu: 2.1

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Active DFGin BLAminus out-in in-in 7KC Type1 299 - 590 0
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
       305        315        325        335 
gshMSHEQFR AALQLVVDPG DPRSYLDNFI KIGEGSTGIV 
       345        355        365        375 
CIATVRSSGK LVAVKKMDLR KQQRRELLFN EVVIMRDYQH 
       385        395        405        415 
ENVVEMYNSY LVGDELWVVM EFLEGGALTD IVTHTRMNEE 
       425        435        445        455 
QIAAVCLAVL QALSVLHAQG VIHRDIKSDS ILLTHDGRVK 
       465        475        485        495 
LSDFGFCAQV SKEVPRRKSL VGTPYWMAPE LISRLPYGPE 
       505        515        525        535 
VDIWSLGIMV IEMVDGEPPY FNEPPLKAMK MIRDNLPPRL 
       545        555        565        575 
KNLHKVSPSL KGFLDRLLVR DPAQRATAAE LLKHPFLAKA 
       585 
GPPASIVPLM RQNRTr
Lower-case residues are disordered in structure.
Mutations: P296G,Q297S,R298H,V299M
Phosphorylation: X474