2W9F

CDK4 (Cyclin-dependent kinase 4)
Group: CMGC
Uniprot: CDK4_HUMAN
Organism: Homo sapiens
Domain boundary: 6 - 295
Resolu: 2.85

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
B Inactive DFGin None out-out out-none No_ligand No_ligand 5 - 295 6
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain B
        10         20         30         40 
matsRYEPVA EIGVGAYGTV YKARDPHSGH FVALKSVRVP 
        53         63         73         83 
NGEEGLPIST VREVALLRRL EAFEHPNVVR LMDVCATSRT 
        93        103        113        123 
DREIKVTLVF EHVDQDLRTY LDKAPPPGLP AETIKDLMRQ 
       133        143        153        163 
FLRGLDFLHA NCIVHRDLKP ENILVTSGGT VKLADFGLAR 
       173        183        193        203 
IYSYQMAlfp vvvTLWYRAP EVLLQSTYAT PVDMWSVGCI 
       213        223        233        243 
FAEMFRRKPL FCGNSEADQL GKIFDLIGlp peddWPRDVS 
       253        263        273        283 
lprgafpprg prpvqSVVPE MEESGAQLLL EMLTFNPHKR 
       293        303 
ISAFRALQHS YLhkdegnpe hhhhhh
Lower-case residues are disordered in structure.
Mutations: G43E,G47E,T172F
Phosphorylation: None