2QI8

SRC (Proto-oncogene tyrosine-protein kinase Src)
Group: TYR
Uniprot: SRC_CHICK
Organism: Gallus gallus
Domain boundary: 267 - 518
Resolu: 2.32

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A None DFGin BLAminus in-in in-none No_ligand No_ligand 257 - 533 14
B Inactive DFGin None out-out none-none No_ligand No_ligand 258 - 533 16
Representative sequence - Chain B
257 267 277 287
ghmqtqglak DAWEIPRESL RLEVKLGQgc fGEVWMGTWN
297 307 317 327
GTTRVAIKTL kpgtmspeAF LQEAQVMKKL RHEKLVQLYA
337 347 357 367
VVSEEPIYIV MEYMSKGCLL DFLKGEMGKY LRLPQLVDMA
377 387 397 407
AQIASGMAYV ERMNYVHRDL RAANILVGEN LVCKVADFGL
417 427 437 447
Arliedneyt arqgakfPIK WTAPEAALYG RFTIKSDVWS
457 467 477 487
FGILLTELTT KGRVPYPGMV NREVLDQVER GYRMPCPPEC
497 507 517 527
PESLHDLMCQ CWRKDPEERP TFEYLQAFLE DYFTSTEPQY

QPGENL
Lower-case residues are disordered in structure.
Mutations: T338M,S345C
Phosphorylation: None